Table 2 .

Changes in each variable in EXTEM

EXTEM	Reference range [11]	0	4 h	8 h	12 h	24 h
CT, s	42–74	67 ± 6	55 ± 5	61 ± 7	60 ± 3	64 ± 6
CFT, s	46–148	111 ± 5	121 ± 11	133 ± 9	120 ± 9	141 ± 7**
MCF, mm	49–71	62 ± 1	61 ± 1	58 ± 1***	56 ± 2*	55 ± 1***
MCE, (G dynes/cm2)/50	105–235	167 ± 6	155 ± 4	139 ± 6***	131 ± 10*	121 ± 5***

Mean ± SEM

CT clotting time CFT clot formation time, MCF maximum clot firmness, MCE maximal clot elasticity;

*p < 0.05, **p < 0.01, ***p < 0.001vs. 0