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TIPE2 inhibits the activation of Wnt/β-catenin pathway in breast cancer cells. MDA-MB-231 cells were infected with TIPE2 or vector for 48 h. (A) The protein expression levels of β-catenin, cyclin D1, and c-Myc were determined by Western blot. (B) The relative protein levels were quantified using Image-Pro Plus 6.0 software. Data are mean ± SD of three independent experiments. *p < 0.05 versus vector group.
