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. 2021 Jan 1;11(1):79–91.

Figure 3.

Figure 3

Tumor cell lysis of CAR-Vγ9Vδ2 T cells in a CAR-dependent antigen-specific manner. A. MUC1-Tn antigen expression level on Jurkat T cells and COSMC-Jurkat T cells assessed by flow cytometry, demonstrating loss of MUC1-Tn expression on COSMC-Jurkat T cells. B. Antigen-specific cytotoxicity of CAR-Vγ9Vδ2 T cells against Jurkat T cells and COSMC-Jurkat T cells at different E:T ratios assayed by flow cytometry. C. Detection of TNF-α, granzyme B, and IFN-γ concentrations in the supernatants from the cytotoxicity assay of CAR-Vγ9Vδ2 T cells against Jurkat T cells and COSMC-Jurkat T cells. Data are presented as mean ± SD (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.