Table 1.

Inhibitory activity against PARP family enzymes

PARPs	Enzyme inhibitory activity (%)
	K-476		XAV939
	1 μmol/L	10 μmol/L	10 μmol/L (or 1 μmol/L*)
PARP1	0	0	84*
PARP2	0	0	99*
PARP3	0	0	3
TNKS1	100	100	100*
TNKS2	100	100	100*
PARP6	0	0	0
PARP7	2	18	17
PARP8	2	0	0
PARP10	8	38	10
PARP11	1	0	37
PARP12	0	3	61