Table 3.
Peripheral and central blood pressure in relation to the serum klotho concentration.
| Characteristics | Klotho groups | P | |||
|---|---|---|---|---|---|
| 1st quartile (n = 179) (37–178 pg/mL) |
2nd quartile (n = 179) (181–382 pg/mL) |
3rd quartile (n = 179) (382–952 pg/mL) |
4th quartile (n = 179) (952–10,957 pg/mL) |
||
| Unadjusted | |||||
| Peripheral SBP, mmHg | 118.0 ± 1.3 | 119.0 ± 1.3 | 120.6 ± 1.3 | 118.1 ± 1.3 | 0.49 |
| Peripheral DBP, mmHg | 76.1 ± 0.8 | 78.3 ± 0.8 | 78.0 ± 0.8 | 76.5 ± 0.8 | 0.18 |
| Peripheral PP, mmHg | 41.9 ± 0.8 | 40.7 ± 0.8 | 42.6 ± 0.8 | 41.6 ± 0.8 | 0.44 |
| Central SBP, mmHg | 115.1 ± 1.3 | 115.9 ± 1.3 | 115.5 ± 1.3 | 116.8 ± 1.3 | 0.82 |
| Central DBP, mmHg | 77.2 ± 0.9 | 79.4 ± 0.9 | 78.0 ± 0.9 | 78.77 ± 0.9 | 0.33 |
| Central PP, mmHg | 37.4 ± 0.7 | 36.0 ± 0.7 | 37.0 ± 0.7 | 37.5 ± 0.7 | 0.36 |
| Adjusted* | |||||
| Peripheral SBP, mmHg | 118.6 ± 1.0 | 118.9 ± 1.0 | 120.2 ± 1.0 | 118.0 ± 1.0 | 0.40 |
| Peripheral DBP, mmHg | 76.7 ± 0.7 | 77.8 ± 0.7 | 77.8 ± 0.7 | 76.5 ± 0.7 | 0.37 |
| Peripheral PP, mmHg | 41.9 ± 0.7 | 41.1 ± 0.7 | 42.4 ± 0.7 | 41.4 ± 0.7 | 0.57 |
| Central SBP, mmHg | 115.8 ± 1.0 | 115.8 ± 1.0 | 115.2 ± 1.0 | 116.5 ± 1.0 | 0.84 |
| Central DBP, mmHg | 77.8 ± 0.7 | 79.1 ± 0.7 | 77.8 ± 0.7 | 78.7 ± 0.7 | 0.49 |
| Central PP, mmHg | 37.4 ± 0.6 | 36.2 ± 0.6 | 36.9 ± 0.6 | 37.3 ± 0.6 | 0.52 |
Values are presented as means ± standard errors. *Values are adjusted for age, sex, body mass index, glomerular filtration rate, hypertension, diabetes status, antihypertensive treatment, current smoking, and alcohol intake.
DBP diastolic blood pressure, PP pulse pressure, SBP systolic blood pressure.