Figure 6.

Depletion of NFBD1 inhibits nasopharyngeal cancer tumor growth and induces apoptosis in vivo. NFBD1 shRNA and NC-shRNA cells were subcutaneously injected into two groups of athymic nude mice (n = 5 for each group). Tumor xenografts were measured once a week with Vernier calipers. (a) Images of tumor-bearing nude mice. (b) The growth curves of NPC cells in tumor xenografts plotted from tumor volumes recorded at different time points. Data are presented as mean ± SD from five mice. (c) Tumor weight was measured after the mice were killed. (d) Representative images of TUNEL staining from each group (400×). *p < 0.05.