Overexpression of miR-142-5p reduces HCC cell viability. Human HCC cell lines HepG2 and SMMC-7721 cells were transfected with miR-142-5p mimic, inhibitor, and corresponding negative control, and then cell viability was analyzed. (A) The relative cell viability in HepG2 cells was significantly decreased by miR-142-5p overexpression, but was statistically increased by miR-142-5p suppression. (B) The relative cell viability in SMMC-7721 cells was markedly decreased by miR-142-5p overexpression, but remarkably was increased by miR-142-5p suppression. miR, microRNA. *p < 0.05 compared to the control group.