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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Neuroimage. 2020 Nov 26;226:117598. doi: 10.1016/j.neuroimage.2020.117598

Table 3.

Multivariate regression model testing associations between pubertal stage, OFC-NAcc FDC, and sex with reward and punishment sensitivity.

Overall Model Reward Sensitivity Punishment Sensitivity
Effect Pillai F p F p F p
ELS 0.02 1.30 .276 2.02 .158 1.73 .190
Age 0.02 1.37 .258 1.70 .195 2.22 .138
Race 0.04 3.14 .046* 4.08 .045* 4.95 .028*
Sex 0.08 6.64 .001* 13.07 .001* 1.17 .282
Pubertal Stage 0.02 1.58 .209 3.12 .079 0.27 .601
OFC-NAcc FDC 0.03 2.16 .110 1.00 .320 1.48 .225
Pubertal Stage × Sex 0.01 0.25 .780 0.12 .731 0.17 .683
OFC-NAcc × Sex 0.06 4.81 .009* 3.07 .082 9.47 .002*
 OFC-NAcc Simple Slopes:
  Males t=−3.11 .002*
  Females t=1.06 .289

Note:

*

p<.05.

ELS=early life stress cumulative severity; FDC=fiber density and cross-section; OFC=orbitofrontal cortex; NAcc=nucleus accumbens. Reward sensitivity model: adjusted R2=.11, F(9, 144)=3.15, p=.002. Punishment sensitivity model: adjusted R2=.08, F(9, 144)=2.41, p=.014. Age, ELS severity, race, and scanner acquisition were included as covariates; Race was coded as 1=White, 2=Racial-ethnic minority; Sex was coded as 1=male, 2=female.