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. 2021 Jan 27;11(2):96. doi: 10.1007/s13205-021-02646-6

Table 1.

The unigenes involved in terpenoid backbone and diterpenoid biosynthesis

Pathways Abbreviation of gene Name of the gene Enzyme no. Number of genes
MVA AACT Acetyl-CoA C-acetyltransferase K00626 14
HMGS Hydroxymethylglutaryl-CoA synthase K01641 1
HMGR Hydroxymethylglutaryl-CoA reductase (NADPH) K00021 5
MVK Mevalonate kinase K00869 1
PMK Phosphomevalonate kinase K00938 3
MVD Diphosphomevalonate decarboxylase K01597 1
MEP DXS 1-Deoxy-D-xylulose-5-phosphate synthase K01662 14
DXR 1-Deoxy-D-xylulose-5-phosphate reductoisomerase K00099 1
ISPD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase k00991 2
ISPE 4-Diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 2
ISPF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 1
ISPG (E)-4-Hydroxy-3-methylbut-2-enyl-diphosphate synthase K03526 1
ISPH 4-Hydroxy-3-methylbut-2-en-1-yl diphosphate reductase K03527 1
IDI Isopentenyl-diphosphate delta-isomerase K01823 3
FDPS Farnesyl diphosphate synthase K00787 5
FDP regulatory pathway FNTP Protein farnesyl transferase subunit beta K05954 7
FACE2 Prenyl protein peptidase K08658 4
STE24 STE24 endopeptidase K06013 7
ICMT Protein-S-isoprenylcysteine O-methyltransferase K00587 1
PCME Prenylcysteine alpha-carboxyl methylesterase K15889 11
FCLY Prenylcysteine oxidase/farnesylcysteine lyase K05906 2
FLDH NAD + -dependent farnesol dehydrogenase K15891 2
FOLK Farnesol kinase K15892 2
GGPPS Geranylgeranyl diphosphate synthase, type II K13789 8
Diterpenoid skeleton synthetic pathway CDPS ent-Copalyl diphosphate synthase K04120 18
KS ent-Kaurene synthase K04121 14
KO ent-Kaurene oxidase K04122 8
Total 139