Table 4.
Multivariate analysis of prognostic factors using the Cox-regression model (including 8th AJCC pathological prognostic staging).
| Variables | BCSS | OS | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Age (years) | ||||
| ≥50 vs.<50 | 1.060 (0.742–1.516) | 0.748 | 1.438(1.048–1.974) | 0.024 |
| Race/ethnicity | ||||
| Non-Hispanic Black vs. Non-Hispanic White | 1.291 (0.837–1.990) | 0.248 | 1.298(0.886–1.904) | 0.181 |
| Hispanic (All Races) vs. Non-Hispanic White | 0.813 (0.440–1.504) | 0.510 | 1.029(0.627–1.691) | 0.909 |
| Other vs. Non-Hispanic White | 0.770 (0.396–1.495) | 0.440 | 0.765(0.419–1.397) | 0.383 |
| Histology | ||||
| ILC vs. IDC | 2.113 (1.089–4.102) | 0.027 | 2.176(1.236–3.832) | 0.007 |
| Other vs. IDC | 0.740 (0.396–1.382) | 0.344 | 0.886(0.539–1.457) | 0.634 |
| AJCC pathological prognostic staging | ||||
| IIIB vs. IIIA | 3.460 (1.802–6.644) | <0.001 | 2.209(1.346–3.625) | 0.002 |
| IIIC vs. IIIA | 6.026(3.115–11.657) | <0.001 | 4.389(2.668–7.219) | <0.001 |
AJCC, American Joint Committee on Cancer; BCSS, breast cancer-specific survival; CI, confidence interval; HR, hazard ratio; IDC, infiltrating ductal carcinoma; ILC, infiltrating lobular carcinoma; OS, overall survival.