Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 27;11:2322. doi: 10.1038/s41598-021-81939-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Urodynamic studies (UDS) demonstrate the physiological function of female rat bladders pre- and post-augmentation with either (A) POC or (B) SIS scaffolds seeded at a specific cellular concentration and ratio with MSC and CD34 + HSPC. Female graft groups are further divided by the absence (S−) or presence (S+) of bladder stones, which, based on our results are thought to alter the bladder’s true capacity. (A, B) Tables display the mean filling capacity (μl) and range in post-augment/pre-augment capacity ratios for each composite graft (n = 5–6 before subsets). The only female rat group to demonstrate post-augment/pre-augment ratios ≥ 0.9 at all seeding levels was F/POC (S−). (C, D) UDS readings are representative of each of the female groups and demonstrate the rise in intravesical pressure (cmH20) leading to a contraction of the bladder.