Figure 5.

Urodynamic testing on male rat bladders pre- and post-augmentation with (A) POC or (B) SIS scaffolds seeded at a specific cellular concentration (cells/cm²) with MSC and CD34 + HSPC at varying ratios. Male graft groups are further divided into S− and S+ animals, separated due to the effect bladder stones may have on the actual bladder capacity. A/B) Tables display the mean filling capacity (μl) and range in post-augment/pre-augment capacity ratios of the bladders (n = 2–6 before subsets). Rats in the M/POC (S−) construct were the only group out of 4 to achieve post-augment/pre-augment ratios over 1.0 × in all seeding groups. (C, D) UDS readings are from a single group individual and are representative of the group as a whole.