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. 2017 Sep 21;25(8):1373–1382. doi: 10.3727/096504017X14878509668646

Figure 5.

Figure 5

Observation of cell proliferation, migration, and invasion after IWR-endo stimulation. (A) Expression of β-catenin in 786-O cells by Western blot analysis. The upregulated expression of β-catenin induced by ANRIL was attenuated after IWR-endo stimulation. (B) Cell proliferation by CCK-8 assay. The promoting effect of ANRIL on cell proliferation of 786-O cells was attenuated after IWR-endo stimulation. Cell migration (C) and cell invasion (D) by Transwell assay. The promoting effects of ANRIL on cell migration and invasion of 786-O cells were both attenuated after IWR-endo stimulation. Data are expressed as mean ± SD of at least three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.