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. 2021 Jan 27;12:611. doi: 10.1038/s41467-020-20595-1

Fig. 9. Summary of features of S. pombe subtelomeres.

Fig. 9

The S. pombe SH region is composed of two parts: the SH-P region with a mosaic of multiple segments, and the SH-D region with multiple blocks and boxes containing deletions and insertions. Colors of bars indicate relative rates of chromosome rearrangement or nucleotide alteration versus PomBase (orange, high rate; blue, low rate). The SH-P region shows high rates of chromosome rearrangement and nucleotide alteration even between the 972 strains (972SD4 and JB22 vs. PomBase), whereas the SH-D region shows lower rates of these changes compared with those in the SH-P region. The SU, boundary, and SA regions and the rap1 and taz1 loci also exhibit medium levels of these changes in the JB strains that are phylogenetically distant from 972. Thus, chromosomal regions around the subtelomeres (and the rap1 and taz1 loci) are prone to genome diversity. Dotted line indicates a region that was unable to be analyzed with the NGS data.