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. 2020 Dec 23;48(12):0300060520979856. doi: 10.1177/0300060520979856

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Construction of the PPI network. (a) PPI network of shared genes. Each dot represents a node. importance of the gene in the network is reflected by the degree of the node which is represented by the number of lines connected to the dot (node). A thicker line reflects a stronger interaction between two nodes. Red points represent up-regulated genes and blue points represent down-regulated genes. (b) The network of key genes selected using the Maximal Clique Centrality algorithm. Important genes are shown in darker colors.

PPI, protein–protein interaction.