TUG1 reverses the miR-145-5p-induced inhibitory effect on proliferation and invasion of GC cells. BGC-823 and SGC-7901 cells were transfected with miR-145-5p, miR-NC, miR-145-5p + NC, or miR-145-5p + TUG1. Cell viability was determined by MTT assay in transfected BGC-823 (A) and SGC-7901 (B) cells at 24, 48, 72, and 96 h. Cell invasiveness was evaluated by Transwell invasion assay in transfected BGC-823 (C) and SGC-7901 (D) cells. *p < 0.05, **p < 0.01.