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. 2017 Nov 2;25(9):1543–1553. doi: 10.3727/096504017X14886444100783

Figure 2.

Figure 2

Effect of sorafenib on the motility and MMP-2 expression of HepG2 and SK-HEP-1 cells. (A, B) Wound healing assay to analyze the migration of HepG2 and SK-HEP-1 cells after treatment with different concentrations of sorafenib (0, 3, 6, and 12 μmol/L). (C) Cells were exposed to 0, 3, 6, and 12 μmol/L sorafenib for 48 h, protein expression of MMP-2 was examined by Western blot. Data represent the mean ± SD of three independent experiments. *p < 0.05, **p < 0.01 compared with the control group.