Table 2.
Severity scale for the classification of anaphylactic reactions (modified from [6, 47]). The classification is made according to the most severe symptoms observed (no symptom is mandatory)
| Grade | Skin and general subjective symptoms | Abdomen | Respiratory tract | Cardiovascular |
|---|---|---|---|---|
| I | Itch | – | – | – |
| Flush | ||||
| Urticaria | ||||
| Angioedema | ||||
| II | Itch | Nausea | Rhinorrhea |
Tachycardia (increase by ≥20/min) |
| Flush | Cramps | Hoarseness | ||
| Urticaria | Vomitus | Dyspnea |
Hypotension (decrease by 20 mm Hg systolic pressure) |
|
| Angioedema | ||||
| Arrhythmia | ||||
| III | Itch | Vomiting | Laryngeal edema | Shock |
| Flush | Defecation | Bronchospasm | ||
| Urticaria | Cyanosis | |||
| Angioedema | ||||
| IV | Itch | Vomiting | Respiratory arrest | Cardiac arrest |
| Flush | Defecation | |||
| Urticaria | ||||
| Angioedema |