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The effect of PDIA6 downregulation on BC cell proliferation in vitro and tumor growth in vivo. (A, B) The Western blot assay showed downregulated PDIA6 in T24 and RT4 cells after transfection of siPDIA6. (C, D) The MTT assay showed that PDIA6 downregulation greatly reduced the proliferative capacity of T24 and RT4 cells. (E, F) The volume and weight of tumors were remarkably decreased after injection of siPDIA6-transfected RT4 cells into nude mice. *p < 0.05.
