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Downregulation of FOXR2 inhibits the activation of the Shh signaling pathway. (A) As shown by the Western blot assay, downregulation of FOXR2 remarkably decreased the protein expression of Shh, Gli1, and Ptch1 in SW480 cells. (B) Relative protein expression levels of Shh, Gli1, and Ptch1 in SW480 cells were measured using analysis software. *p < 0.05.
