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miR-92a suppresses proliferation of AML cells by targeting MTHFD2. HL-60 and THP-1 cells were transfected with either miR-92a mimics or in combination with pcDNA-MTHFD2. (A) CCK-8 analysis of cell viability at indicated time points (0, 24, 48, and 72 h) in transfected HL-60 and THP-1 cells. (B, C) Western blot analysis indicated the level of proliferation-related protein Ki-67 at 48 h in transfected HL-60 (B) and THP-1 cells (C). *p < 0.05 versus controls.
