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Knockdown of TMEM45B inhibited tumor growth in vivo. Infected U2OS cells (1 × 106) were injected subcutaneously into 4-week-old female nude mice. (A) Tumor growth was monitored with calipers once a week for a total of 4 weeks. (B) Tumors were removed and weighed after 20 days. *p < 0.05, compared with the shNC group.
