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. 2017 Sep 21;25(8):1383–1390. doi: 10.3727/096504017X14879366402279

Figure 3.

Figure 3

miR-101-3p overexpression decreased the proliferation and invasion of AGS gastric adenocarcinoma cell lines. (A) miR-101-3p expression was distinctly increased by the miR-101-3p mimic transfection. (B, C) The miR-101-3p mimics and SRF siRNA both reduced the proliferation and invasion of AGS cells. The 60 nM mimic-NC or miR-101-3p mimics were transfected into AGS human gastric adenocarcinoma cell lines. As a comparison, a ctrl-siRNA and a specific siRNA against SRF were also transfected into AGS cells. After incubation for 48 h, miR-101-3p expression was detected with real-time quantitative PCR (qPCR). Cell proliferation was detected with the cell counting kit-8 (CCK-8) assay, and cell invasion was detected with the Transwell invasion assay. *p < 0.05, **p < 0.01 versus mimic-NC or ctrl-siRNA.