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. 2017 Jul 5;25(6):913–921. doi: 10.3727/096504016X14792098307036

Figure 1.

Figure 1

Expression of lncRNA CCAT2 is increased in glioma tissues and cell lines and associates with overall survival in glioma patients. (A) Expression of CCAT2 in human glioma cancer tissues and cell lines; expression of CCAT2 in human glioma tissues was higher than in noncancerous tissues, and lncRNA CCAT2 expression is increased in glioma cancer cell lines compared with normal glioma cell line. (B) Expression of CCAT2 in high-grade gliomas was higher than in low-grade gliomas. (C) High expression of lncRNA CCAT2 predicts a poor prognosis in glioma cancer patients. The relationship between lncRNA CCAT2 and glioma cancer patient survival was estimated using the Kaplan–Meier method and the log-rank test. (D) lncRNA CCAT2 expression is decreased by small interfering RNA (si-CCAT2) in U87 and U251 cells. *p < 0.05 compared with normal control; **p < 0.01 compared with normal control; ***p < 0.001 compared with normal control.