Table 2.
Correlations between ST8SIA4 expression levels and clinicopathological features in cholangiocarcinoma.
| Variables | ST8SIA4 expression level | P-value | ||
|---|---|---|---|---|
| Low | High | |||
| Gender | Male | 35 | 21 | 0.559 |
| Female | 26 | 16 | ||
| Age(y) | <60 | 31 | 18 | 0.500 |
| ≥60 | 30 | 19 | ||
| ALB(U/L) | <28 | 2 | 2 | 0.219 |
| 28–35 | 6 | 8 | 0.228 | |
| >35 | 53 | 27 | 0.130 | |
| HBsAg | No | 29 | 25 | 0.042 |
| Yes | 32 | 12 | ||
| HCVAg | No | 58 | 37 | 0.237 |
| Yes | 3 | 0 | ||
| Tumor number |
Single | 32 | 23 | 0.234 |
| Multiple | 29 | 14 | ||
| Tumor size | <5cm | 25 | 17 | 0.393 |
| ≥5cm | 36 | 20 | ||
| TNM stage | I–III | 53 | 28 | 0.127 |
| IV | 8 | 9 | ||
| Vascular invasion |
No | 33 | 19 | 0.478 |
| Yes | 28 | 18 | ||
| LN metastasis |
No | 44 | 18 | 0.030 |
| Yes | 17 | 19 | ||
The chi-square tests were adopted to analyze correlation between ST8SIA4 levels and clinicopathological features in cholangiocarcinoma. The mean value of expression level was used as the cutoff. Bold values had statistical significance. intrahepatic cholangiocarcinoma=84, perihilar cholangiocarcinoma=14.