. 2021 Jan 14;11:616797. doi: 10.3389/fmicb.2020.616797

TABLE 1.

In vitro antibacterial activity of TEL compared with that of various antibiotics against E. faecalis isolates.

Antibiotic	No. isolates	Resistance rate (%)	MIC (μg/mL) breakpoints	NO.	TEL MIC (μg/mL)						ERY MIC (μg/mL)
					≤0.5	1	2	4	≥8	MIC₅₀/MIC₉₀	≤0.5	1–4	≥8	MIC₅₀/MIC₉₀
Total	280	–	–	–	116	7	27	97	33	2/8	10	58	212	>256/>256
Ampicillin	275	0.4	≤8	274	130	6	26	83	29	2/8	8	55	211	>256/>256
			≥16	1	0	0	0	1	0	4/4	0	0	1	–
Vancomycin	280	0	≤4	278	115	7	27	96	33	2/8	10	58	210	>256/>256
			8–16	2	1	0	0	1	0	0.125/4	0	0	2	>256/>256
			≥32	0	0	0	0	0	0	–	0	0	0	–
Tetracycline	276	83.7	≤4	39	33	3	1	2	0	0.06/1	7	17	15	4/>256
			8	6	3	0	0	2	1	0.06/4	1	1	4	128/>256
			≥16	231	79	4	25	91	32	4/8	2	39	190	>256/>256
Doxycycline	280	78.9	≤4	40	36	1	2	1	0	0.06/0.125	7	19	14	2/>256
			8	19	7	2	3	6	1	2/4	1	2	16	128/>256
			≥16	221	73	4	22	90	32	4/8	2	37	182	>256/>256
Minocycline	280	73.2	≤4	43	37	2	2	2	0	0.06/2	7	21	15	2/>256
			8	32	11	0	9	9	3	2/4	1	5	26	>256/>256
			≥16	205	68	5	16	86	30	4/8	2	32	171	>256/>256
Ciprofloxacin	252	26.6	≤1	151	68	3	11	51	18	2/8	5	25	121	>256/>256
			2	34	22	1	2	8	1	0.125/4	1	12	21	128/>256
			≥4	67	24	3	14	20	6	2/8	2	12	53	>256/>256
Nitrofurantoin	254	1.2	≤32	247	102	6	26	84	29	2/8	9	52	186	>256/>256
			64	4	2	0	0	2	0	0.5/4	0	0	4	>256/>256
			≥128	3	3	0	0	0	0	0.03/0.25	0	2	1	4/>128
Linezolid	280	5.4	≤2	214	87	6	21	75	25	2/8	9	44	161	>256/>256
			4	51	23	1	6	17	4	2/4	1	11	39	>256/>256
			≥8	15	6	0	0	5	4	4/8	0	3	12	>256/>256

MIC, minimum inhibitory concentration; TEL, telithromycin; ERY, erythromycin; MIC₅₀/MIC₉₀, the MIC values for 50% or 90% of bacterial growth inhibition.