Table 1.
Segetalin cyclopeptides with their sequences and biological activities.
Peptide names | Peptide sequence | Cytotoxic activity | Pharmacological activities | Anti-infective activities |
---|---|---|---|---|
Segetalin A | Cyclo(-Gly-Val-Pro-Val-Trp-Ala-) | — | Estrogenic | |
Segetalin B | Cyclo(-Gly-Val-Ala-Trp-Ala-) | — | Estrogenic, Contractile | |
Segetalin C | Cyclo(-Gly-Leu-His-Phe-Ala-Phe-Pro-) | — | ||
Segetalin D | Cyclo(-Gly-Leu-Ser-Phe-Ala-Phe-Pro-) | — | ||
Segetalin E | Cyclo(-Gly-Tyr-Val-Pro-Leu-Trp-Pro-) | On P-388 cells, DLA cells, EAC cells | Antihelimintic | |
Segetalin F | Cyclo(-Tyr-Ser-Ser-Lys-Pro-Ser-Ala-Ser) | Vasorelaxant | ||
Segetalin G | Cyclo(-Gly-Val-Lys-Tyr-Ala) | Estrogenic, Vasorelaxant | ||
Segetalin H | Cyclo(-Gly-Tyr-Arg-Phe-Ser) | Estrogenic, Vasorelaxant | ||
Segetalin J | Cyclo(-Phe-Gly-Thr-His-Gly-Leu-Pro-Ala-Pro-) | — | ||
Segetalin K | Cyclo(-Gly-Arg-Val-Lys-Ala-) | — |