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. 2021 Jan 14;11:600856. doi: 10.3389/fendo.2020.600856

Table 3.

Dichotomin cyclopeptides with their sequences and biological activities.

Peptide names Peptide sequence Cytotoxic activity Pharmacological activities Anti-infective activities
Dichotomin A Cyclo(-Gly-Thr-Phe-Leu-Tyr-Val) +
Dichotomin B Cyclo(-Gly-Thr-Phe-Leu-Tyr-Thr) +
Dichotomin C Cyclo(-Gly-Thr-Phe-Leu-Tyr-Ala) +
Dichotomin D Cyclo(-Gly-Val-Gly-Phe-Tyr-Ile) Cyclooxygenase inhibitor
Dichotomin E Cyclo(-Gly-Tyr-Ala-Phe-Ala) +
Dichotomin F Cyclo(-Pro-Tyr-Phe-Val-Leu-Pro-Ser-Val-Tyr) Cyclooxygenase inhibitor
Dichotomin G Cyclo(-Pro-Leu-Pro-Ile-Pro-Pro-Phe-Tyr-Ser) Cyclooxygenase inhibitor
Dichotomin H Cyclo(Ala-Pro-Thr-Phe-Tyr-Pro-Leu-Ile) +
Dichotomin I Cyclo(-Val-Pro-Thr-Phe-Tyr-Pro-Leu-Ile) +
Dichotomin J Cyclo(-Gly-Ile-Phe-Leu-Tyr-Ala) antibacterial, antifungal, anthelmintic