Table 3.
Dichotomin cyclopeptides with their sequences and biological activities.
| Peptide names | Peptide sequence | Cytotoxic activity | Pharmacological activities | Anti-infective activities |
|---|---|---|---|---|
| Dichotomin A | Cyclo(-Gly-Thr-Phe-Leu-Tyr-Val) | + | ||
| Dichotomin B | Cyclo(-Gly-Thr-Phe-Leu-Tyr-Thr) | + | ||
| Dichotomin C | Cyclo(-Gly-Thr-Phe-Leu-Tyr-Ala) | + | ||
| Dichotomin D | Cyclo(-Gly-Val-Gly-Phe-Tyr-Ile) | Cyclooxygenase inhibitor | ||
| Dichotomin E | Cyclo(-Gly-Tyr-Ala-Phe-Ala) | + | ||
| Dichotomin F | Cyclo(-Pro-Tyr-Phe-Val-Leu-Pro-Ser-Val-Tyr) | Cyclooxygenase inhibitor | ||
| Dichotomin G | Cyclo(-Pro-Leu-Pro-Ile-Pro-Pro-Phe-Tyr-Ser) | Cyclooxygenase inhibitor | ||
| Dichotomin H | Cyclo(Ala-Pro-Thr-Phe-Tyr-Pro-Leu-Ile) | + | ||
| Dichotomin I | Cyclo(-Val-Pro-Thr-Phe-Tyr-Pro-Leu-Ile) | + | ||
| Dichotomin J | Cyclo(-Gly-Ile-Phe-Leu-Tyr-Ala) | antibacterial, antifungal, anthelmintic |