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. 2021 Jan 14;8:621269. doi: 10.3389/fbioe.2020.621269

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Copyright © 2021 Lecca.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Numerical simulation of the system defined by Equations (15) and (16) with E₀ = 0, E_max = 100, k₁ = 0.005, k₂ = 0.0004, EC₅₀ = 15, h = 0.001, k = 1, A = 0.001, B = 0.001. As shown later, numerical simulations for times greater than 500 time units, shows that after the first 500 time units the oscillatory behavior disappears to give way to a plateau.