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. 2021 Jan 14;8:621269. doi: 10.3389/fbioe.2020.621269

Figure 5.

Figure 5

Numerical simulation of the system defined by Equations (15) and (16) with E0 = 0, Emax = 100, k1 = 0.005, k2 = −0.0004, EC50 = 15, h = 0.001, k = 1, A = 0.001, B = 0.001. A negative value of k2 causes the concentration curve to assume an increasing monotone trend, while a positive value of k2 causes the curve to reach a plateau after an initial oscillatory behavior.