Table 1. Patient, Donor, and Transplant Characteristics.
Characteristic | No. (%) |
---|---|
Patient age, median (range), y | 31 (17-56) |
Men | 27 (65.9) |
Male donor | 20 (48.8) |
Haploidentical donor | 32 (78.0) |
HLA-matched relative | 9 (22.0) |
Donor-recipient gender | |
FF | 9 (22.0) |
MM | 19 (46.3) |
FM | 10 (24.4) |
MF | 3 (7.3) |
Stem cell source | |
PBSC | 41 (100) |
Diagnosis | |
ALL | 18 (43.9) |
AML | 17 (41.5) |
Other | 6 (14.6) |
Disease status at transplant | |
CR | 37 (90.2) |
PR | 2 (4.9) |
Progressive | 2 (4.8) |
Conditioning regimen | |
MAC | 40 (97.6) |
RIC | 1 (2.4) |
Use of ATG | |
Yes | 32 (78.0) |
No | 9 (22.0) |
Prior acute graft-vs-host disease | |
No | 8 (19.5) |
Grade I to II | 21 (51.2) |
Grade III to IV | 12 (29.3) |
Abbreviations: ALL, acute lymphoid leukemia; AML, acute myeloid leukemia; ATG, antithymoglobuline; CR, complete remission; FF, female to female; FM, female to male; HLA, human leukocyte antigen; MAC, myeloablative conditioning; MF, male to female; MM, male to male; PBSC, peripheral blood stem cell; PR, partial remission; RIC, reduced intensity conditioning.