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. 2021 Jan 27;4(1):e2034890. doi: 10.1001/jamanetworkopen.2020.34890

Table 2. NIH Funding for 2008 and 2019 and Proportion of Total NIH Funding.

Disease category NIH spending, No. (%), $ (in millions) Change %
2008 (N = 37 735)a 2019 (N = 39 420)
Total 21 512 (57.0) 23 680 (60.1) 10
Infection
Total 4438 (11.8) 4075 (10.3) –8
HIV/AIDS 3770 (10.0) 3037 (7.7) –19
STIs, excluding HIV 315 (0.8) 354 (0.9) 12
Tuberculosis 183 (0.5) 488 (1.2) 167
Malaria 170 (0.5) 196 (0.5) 15
GI
Total 2924 (7.7) 3336 (8.5) 14
Digestive diseases 1836 (4.9) 2173 (5.5) 18
Chronic kidney disease 673 (1.8) 649 (1.6) –4
Cirrhosis 310 (0.8) 351 (0.9) 13
Inflammatory bowel disease 104 (0.3) 163 (0.4) 56
Other
Total 2792 (7.4) 3125 (7.9) 12
Urologic diseases 687 (1.8) 546 (1.4) –21
Injuries 597 (1.6) 897 (2.3) 50
Oral disorders 596 (1.6) 613 (1.6) 3
Perinatal disordersb 578 (1.5) 784 (1.9) 36
Interpersonal violence 236 (0.6) 141 (0.4) –40
Self-harm 50 (0.1) 117 (0.3) 133
Sudden infant death syndrome 37 (0.1) 11 (<0.1) –71
Psoriasis 10 (<0.1) 16 (<0.1) 55
Cardiovascular
Total 2610 (6.9) 2394 (6.1) –8
Ischemic heart disease 1567 (4.2) 1443 (3.7) –8
Other cardiovascular diseases 704 (1.9) 685 (1.7) –3
Hypertension 339 (0.9) 266 (0.7) –21
Mental health
Total 2557 (6.8) 3056 (7.8) 20
Drug use disorders 1296 (3.4) 1621 (4.1) 25
Alcohol use disorders 582 (1.5) 556 (1.4) –4
Depressive disorders 518 (1.4) 578 (1.5) 12
Autism 152 (0.4) 290 (0.7) 91
Eating disorders 9 (<0.1) 11 (<0.1) 22
Cancer
Total 2545 (6.7) 2560 (6.5) 1
Breast cancer 935 (2.5) 709 (1.8) –24
Prostate cancer 373 (1.0) 263 (0.7) –30
Colon and rectum cancer 353 (0.9) 294 (0.7) –17
Non-Hodgkin lymphoma 248 (0.7) 248 (0.6) 0
Lung cancer 218 (0.6) 419 (1.1) 93
Ovarian cancer 124 (0.3) 168 (0.4) 36
Liver cancer 115 (0.3) 127 (0.3) 11
Cervical cancer 89 (0.2) 106 (0.3) 19
Leukemia 50 (0.1) 178 (0.5) 255
Hodgkin lymphoma 21 (0.1) 12 (<0.1) –42
Uterine cancer 21 (0.1) 36 (0.1) 75
Neurologic
Total 1701 (4.5) 3451 (8.8) 103
Alzheimer and dementias 530 (1.4) 2398 (6.1) 352
Stroke 381 (1.0) 350 (0.9) –8
Schizophrenia 321 (0.8) 263 (0.7) –18
Multiple sclerosis 218 (0.6) 111 (0.3) –49
Parkinson disease 196 (0.5) 224 (0.6) 14
Motor neuron disease 55 (0.1) 105 (0.3) 90
Endocrine
Total (diabetes) 1390 (3.7) 1099 (2.8) –21
Respiratory
Total 533 (1.4) 571 (1.4) 7
Asthma 317 (0.8) 313 (0.8) –1
Pneumonia 120 (0.3) 146 (0.4) 22
COPD 97 (0.3) 112 (0.3) 16
Sensory
Total (otitis media) 23 (0.1) 13 (<0.1) –44

Abbreviations: COPD, chronic obstructive pulmonary disease; GI, gastrointestinal; STI, sexually transmitted infection.

a

Adjusted to 2019 dollars.

b

Includes neonatal disorders.