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. 2020 Aug 20;106(2):130–136. doi: 10.1136/archdischild-2020-318913

Table 2.

Clinical history and examination findings among neonates and young infants

Characteristic Ages 0–6 days Ages 7–59 days
No meningitis (n=3469) Meningitis (n=39) P value* No meningitis (n=1259) Meningitis (n=42) P value*
Bulging fontanel
 No 3419 (99) 37 (95) <0.001 1233 (98) 33 (79) <0.001
 Yes 15 (0.4) 2 (5.1) 11 (0.9) 9 (21)
 Missing 35 (1.0) 0 (0) 15 (1.2) 0 (0)
Convulsions
 No 3269 (94) 34 (87) 0.063 1162 (92) 31 (74) <0.001
 Yes 168 (4.8) 5 (13) 82 (6.5) 11 (26)
 Missing 32 (0.9) 0 (0) 15 (1.2) 0 (0)
Axillary temperature (°C)
 <36 1061 (31) 4 (10) 0.021 77 (6.1) 1 (2.4) 0.269
 36–38.9 2202 (63) 30 (77) 1092 (87) 35 (83)
 ≥39 199 (5.7) 5 (13) 89 (7.1) 6 (14)
 Missing 7 (0.2) 0 (0) 1 (0.1) 0 (0)
Agitation/irritability
 No 3375 (97) 33 (85) <0.001 1198 (95) 36 (86) 0.002
 Yes 59 (1.7) 6 (15) 46 (3.7) 6 (14)
 Missing 35 (1.0) 0 (0) 15 (1.2) 0 (0)
History of fever†
 No 2086 (60) 14 (36) 0.006 470 (37) 9 (21) 0.074
 Yes 1350 (39) 25 (64) 774 (61) 33 (79)
 Missing 33 (1.0) 0 (0) 15 (1.1) 0 (0)
Drowsy, lethargic or unconscious
 No 2626 (76) 27 (69) 0.466 1048 (83) 31 (74) 0.148
 Yes 808 (23) 12 (31) 196 (16) 11 (26)
 Missing 35 (1.0) 0 (0) 15 (1.2) 0 (0)
Abnormal cry
 No 2489 (72) 33 (85) 0.093 846 (67) 31 (74) 0.587
 Yes 945 (27) 5 (13) 118 (9.4) 4 (9.5)
 Missing 35 (1.0) 1 (2.6) 295 (23) 7 (!7)

Data are n (%).

Group percentages may not add to 100% due to rounding off.

*Univariate comparison of characteristics.

†Elevated tactile temperature as reported by the parent or guardian.