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. 2020 Dec 2;92(2):158–164. doi: 10.1136/jnnp-2020-324266

Table 3.

Assessment scores of non-motor symptoms in patients with late onset depressive disorder (LOD) and healthy controls (HC)

Assessment LOD (n=36)* HC (n=30)* P value
RBDSQ mean (SD) 4.3 (3.2) 2.1 (2.1) 0.001
RBD1Q “yes” n (%) 10 (27.8) 2 (6.7) 0.02
SCOPA-AUT mean (SD) 14.9 (8.7) 7.7 (4.9) <0.001
PDSS mean (SD) 98.1 (24.4) 127.6 (13.1) <0.001
UPSIT mean (SD) 30.7 (5.7) 29.5 (6.6) 0.43
MoCA mean (SD) 26.0 (3.6) 26.5 (2.7) 0.51
FAB mean (SD) 17.1 (1.1) 17.0 (1.3) 0.85
LARS mean (SD) −23.3 (9.6) −27.0 (4.7) 0.04
PHQ-9 mean (SD) 9.1 (6.3) 1.4 (1.9) 0.02
HADS-D mean (SD) 7.1 (4.6) 1.2 (1.0) <0.001
HADS-A mean (SD) 9.6 (5.1) 2.8 (2.8) <0.001

Independent samples t test, Mann-Whitney U test and Fisher’s exact.

*Three LOD did not complete the Frontal Assessment Battery (FAB) and one HC did not complete the PDSS.

HADS, Hospital Anxiety and Depression Scale; HADS-A, HADS anxiety subscale; HADS-D, HADS depression subscale; LARS, Lille Apathy Rating Scale; MoCA, Montreal Cognitive Assessment; PDSS, Parkinson’s Disease Sleep Scale; PHQ-9, Patient Health Questionnaire-9; RBD1Q, REM Sleep Behaviour Disorder Single-Question Screen; RBDSQ, The REM Sleep Behaviour Disorder Screening Questionnaire; SCOPA-AUT, Scales for Outcomes in Parkinson’s Disease-Autonomic; UPSIT, University of Pennsylvania Smell Identification Test.