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Number of patients lost to follow-up. The number of patients lost to follow-up is shown for each assessment. The blue lines represent patients receiving edaravone and edaravone–edaravone; the yellow lines represent patients receiving placebo, and the blue dashed lines represent patients receiving placebo–edaravone. ALSFRS-R, Amyotrophic Lateral Sclerosis Functional Rating Scale—Revised; MiToS, Milano-Torino staging.
