Table 2.
Sensitivity, specificity, positive (PPV) and negative predictive values (NPV) for mild and moderate/severe cognitive impairment, as defined by the MoCA, for different cut-offs on the AMTS
| AMTS cut-off | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | ||
|---|---|---|---|---|---|---|
| Mild cognitive impairment (MoCA <26) | ||||||
| <10 | 83.4% (76.8–88.8) | 72.7% (39.0–94.0) | 97.8% (93.8–99.6) | 22.9% (10.4–40.1) | ||
| <9 | 61.3% (53.4–68.9) | 100% (71.5–100) | 100% (96.4–100) | 14.9% (7.7–25.0) | ||
| <8 | 44.8% (37.0–52.8) | 100% (71.5–100) | 100% (95.1–100) | 10.9% (5.6–18.7) | ||
| <7 | 35.0% (27.7–42.8) | 100% (71.5–100) | 100% (93.7–100) | 9.4% (4.8–16.2) | ||
| <6 | 20.2% (14.4–27.2) | 100% (71.5–100) | 100% (89.4–100) | 7.8% (4.0–13.5) | ||
| Moderate/severe cognitive impairment (MoCA <18) | ||||||
| <10 | 92.4% (84.9–96.9) | 34.1% (24.0–45.4) | 61.2% (52.5–69.3) | 80.0% (63.1–91.6) | ||
| <9 | 85.9% (77.0–92.3) | 74.4% (63.6–83.4) | 79.0% (69.7–86.5) | 82.4% (71.8–90.3) | ||
| <8 | 72.8% (62.6–81.6) | 92.7% (84.8–97.3) | 91.8% (83.0–96.9) | 75.2% (65.7–83.3) | ||
| <7 | 59.8% (49.0–69.9) | 97.6% (91.5–99.7) | 96.5% (87.9–99.6) | 68.4% (59.1–76.7) | ||
| <6 | 35.9% (26.1–46.5) | 100% (95.6–100%) | 100% (89.4–100) | 58.2% (49.6–66.4) | ||