Table 1.
Baseline measure | Latest follow up | P value | Matched pairs n (%) | |
Cohort of 128 patients with T2D. Mean (SD) duration of diet 23 (16.8) months | ||||
Age (years) | 63 (54, 73) | – | – | – |
Weight (Kg) | 99.7 (86.2, 109.3) | 91.4 (79, 101.1) | <0.001 | 124 (96.9) |
HbA1c (mmol/mol) | 65.5 (55, 82) | 48 (43, 55) | <0.001 | 127 (99) |
Serum cholesterol (mmol/L) | 4.9 (4.1, 5.7) | 4.4 (3.8, 5.0) | <0.001 | 83 (64.8) |
HDL cholesterol (mmol/L) | 1.2 (1.0, 1.3) | 1.3 (1.0, 1.5) | <0.001 | 96 (75.0) |
Chol/HDL ratio | 4.0(3.0,5.1) | 3.7(2.9,4.4) | <0.001 | 83(64.8) |
Triglyceride (mmol/L) | 2.6 (1.6, 3.2) | 1.7 (1.0, 2.1) | <0.001 | 85 (66.4) |
Systolic BP (mmHg) | 144 (135, 151) | 133 (126, 140) | <0.001 | 95 (74.2) |
Diastolic BP (mmHg) | 83.1 (78, 90) | 78 (70, 82) | <0.001 | 95 (74.2) |
Sub–cohort of 45 patients with T2D diagnosed >72 months before introduction to this service | ||||
Age (years) | 67 (57, 75) | – | – | – |
Weight (Kg) | 96.2 (86.2, 106.0) | 86.9 (76.9, 95.4) | <0.001 | 44 (97.8) |
HbA1c (mmol/mol) | 73 (62, 84) | 49 (45, 56) | <0.001 | 45 (100) |
Serum cholesterol (mmol/L) | 4.6 (3.9, 5.1) | 4.2 (3.6, 4.6 | 0.01 | 31 (68.9) |
HDL cholesterol (mmol/L) | 1.1 (0.8, 1.4) | 1.2 (1.0, 1.4) | 0.039 | 35 (77.8) |
Triglyceride (mmol/L) | 2.8 (1.7, 3.2) | 1.7 (1.1, 2.2) | <0.001 | 34 (75.6) |
Systolic BP (mmHg) | 138 (130, 141) | 131 (122, 139) | 0.004 | 30 (66.7) |
Diastolic BP in mmHg | 79 (76, 80) | 76 (70, 80) | 0.053 | 30 (66.7) |
Sub–cohort of 53 patients with T2D, aged 65 or older at the introduction to this service | ||||
Age (years) | 75 (70, 80) | – | – | – |
Weight (Kg) | 91.8 (81.3, 100.8) | 83.3 (74, 91.8) | <0.001 | 50 (94.3) |
HbA1c (mmol/mol) | 64 (56, 80) | 49 (45, 56) | <0.001 | 53 (100) |
Serum cholesterol (mmol/l) | 4.7 (4.0, 5.5) | 4.4 (3.6, 4.9) | 0.011 | 31 (58.6) |
HDL cholesterol (mmol/L) | 1.3 (1.0, 1.4) | 1.3 (1.1, 1.4) | 0.446 | 38 (71.7) |
Triglyceride in (mmol/L) | 2.4 (1.6, 3.0) | 1.6 (1.0, 2.2) | <0.001 | 36 (67.9) |
Systolic BP (mmHg) | 143 (132, 150) | 134 (129, 140) | <0.001 | 38 (71.7) |
Diastolic BP (mmHg) | 80 (76, 80) | 76 (70, 80) | 0.033 | 38 (71.7) |
Cohort of 71 people with Prediabetes Mean (SD) duration of diet 22 (17.4) months | ||||
Age (years) | 65 (59, 73) | – | – | – |
Weight (Kg) | 90.6 (78.0, 99.0) | 82.2 (71.8, 89.6) | <0.001 | 71 (100) |
HbA1c (mmol/mol) | 44 (43, 45) | 39 (38, 41) | <0.001 | 70 (98.5) |
Serum cholesterol (mmol/L) | 5.4 (4.6, 6.0) | 5.1 (4.3, 5.6) | 0.008 | 49 (72.1) |
HDL cholesterol (mmol/L) | 1.3 (1.1, 1.5) | 1.4 (1.2, 1.6) | 0.010 | 49 (72.1) |
Triglyceride (mmol/L) | 1.9 (1.2, 2.4) | 1.2 (0.7, 1.5) | <0.001 | 33 (48.5) |
Systolic BP (mmHg) | 141 (130, 151) | 131 (124, 138) | <0.001 | 51 (75.0) |
Diastolic BP (mmHg) | 83 (78, 90) | 77 (72, 80) | <0.001 | 51 (75.0) |
The results shown as median (IQR) unless otherwise stated.
BP, blood pressure; T2D, type 2 diabetes.