Table 1.

Univariate and multivariate cox regression analysis of acute myeloid leukemia patients (n = 241)

Variable	Univariate analysis			Multivariate analysis
	HR	95% CI	P value	HR	95% CI	P value
Cytogenetic category
chr –5, –7	0.69	0.21–2.30	0.54
chr –5, –7, + 8	0.54	0.12–2.44	0.43
chr –7	0.63	0.21–1.93	0.42
11q23	0.32	0.10–1.08	0.07
chr + 21	0.09	0.02–0.51	0.01	0.09	0.02–0.51	0.01
chr 5q–	0.94	0.10–8.43	0.95
chr 7q–	2.92	0.32–26.83	0.34
chr + 8	0.36	0.12–1.12	0.08
Diploid	0.24	0.09–0.66	0.01	0.23	0.08–0.64	< 0.01
Inv(9)	0.64	0.12–3.53	0.61
ssInv(16)	0.05	0.01–0.20	0.00	0.05	0.01–0.18	< 0.01
Miscellaneous	0.30	0.11–0.85	0.02	0.30	0.11–0.84	0.02
t(6;9)	0.32	0.08–1.29	0.11
t(8;21)	0.06	0.01–0.27	0.00	0.06	0.01–0.27	< 0.01
FLT3
ITD	1.22	0.86–1.73	0.26
D835	0.75	0.43–1.29	0.30
Any	1.21	0.86–1.69	0.28
NPM1	1.07	0.71–1.61	0.74
DNMT3A	0.94	0.46–1.93	0.87
IDH
IDH1	0.76	0.43–1.35	0.35
IDH2	1.50	0.88–2.56	0.13
Any	1.03	0.67–1.58	0.91
P53	2.50	1.14–5.55	0.02
RAS	0.68	0.45–1.04	0.07
PTPN11	0.53	0.21–1.32	0.17
TET2	1.62	0.89–2.87	0.11
H3K27Me3
Continuous	0.74	0.58–0.94	0.01	0.74	0.57–0.95	0.02