Table 3.

A total of 205 differentially expressed genes were found in T47D cells after GOLPH3L knockdown

Compared group	Upregulated genes	Downregulated genes
NC--si	133	72
	CP, KRT10, PAPSS2, CASP7, UNC5B, AKR1C2, SPRY4, CHST14, FGFR3, SLC6A14, LRRC55, ILF3-AS1, EXOC3-AS1, APLNR, CDK14, AKR1C1, IFI6, OAS2, AXIN2, ZNF702P, MAN1B1-AS1, IFIT1, C2CD4A, AKR1C3, MPV17 L, HABP4, ZCCHC24, PCP4 L1, RASD2, TUB, CRH, STMN3, PALMD, GRIK4, CHD5, FLJ37453, HOXB7, SLC16A10, STEAP4, ARAP3, LOC100132249, SSTR2, SLC5A1, EGR3, ENSG00000261040.2, OASL, ADAM19, TDO2, GAREM2, ENSG00000261071.1, CEACAM1, THEM5, WFDC21P, ADGRA2, ZNF98, PPP1R1B, CDSN, IFI44, SMCO4, SLC22A31, PCDH20, GDF1, COLCA1, C1orf220, B3GNT3, ORM1, ENSG00000254024.1, ADORA1, IFI27, CMPK2, GLTPD2, CCDC177, MYEOV, ENSG00000269962.1, PTCHD1, ENSG00000266795.2, STRA6, RHBDL3, FLJ36000, ANG, RAMP2-AS1, PYDC1, TBXA2R, NELL2, LOC100996419, DLG5-AS1, SLC2A4, GAPDHP43, MYLK-AS1, VGF, EDN2, AMPD3, CNTFR, LOXL4, INSM1, ENSG00000251417.1, KCNB1, ST7-AS1, HMGB1P1, EIF4HP1, GPRC5B, ETV1, ENSG00000233029.3, SNX25P1, ENSG00000273284.1, LINC01023,4-Sep, OGFRP1, TUBB2B, C1S, ENSG00000270964.1, F11-AS1, ENSG00000256982.1, C11orf45, ENSG00000261693.1, F10, ENSG00000236514.1, ZNF663P, TOLLIP-AS1, ALOX12B, TNFAIP8 L3, UNC5CL, VANGL2, ENSG00000269289.1, FRMPD3, PPP1R14BP3, LINC00865, USH1G, ACOT11, HEPHL1, ATP13A4, MUC4, NKX1–2	CLDN1, STC2, FAM65C, CRIM1, PIK3CB, CNOT6, VAPA, REEP3, PON2, AVL9, TMEM45B, VAMP3, KRAS, GOLPH3L, TAF9B, ATP13A2, OLR1, EFNB2, LMBRD1, MAP 6D1, TGFB2, ANXA3, PHACTR1, SHISA2, SH3RF1, USP2, POLR3G, ANKFN1, FSIP2, SAP30 L-AS1, TGFB2-OT1, GRIK1, ACPP, SYNPO, BCHE, ABCC13, PDZK1, DNAH5, SCART1, CCL2, SYBU, ECHDC1, ENSG00000260037.1, LOC100288911, ENSG00000265242.1, SERPINE1, ADIPOQ, ENSG00000254343.2, NWD2, CCR2, KIF5C, OTOR, TCF4, GPR183, SNORD12B, LINC00312, MUM1 L1, TAB3-AS1, CYP1A1, ENSG00000267896.1, PSG9, SPOCK2, ENSG00000269680.1, SLCO2A1, ADM, ENSG00000255142.1, PLAC4, ENSG00000257193.1, ENSG00000231868.1, CRYGS, IL16, ENSG00000236933.1

Legends: KEGG pathways of different metabolites that were altered significantly after GOLPH3L silencing, p-values< 0.05