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. 2021 Jan 28;9:7. doi: 10.1186/s40170-021-00243-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Association between RNF115 expression and LUAD prognosis. a Expressions of RNF115 in normal or LUAD tumorous tissues were analyzed based on TCGA database. b Comparison of the survival probability between LUAD patients with high and low expressions of RNF115 over 200 months by Kaplan-Meier plotting. c–e Analysis of RNF115 gene expression in 25 paired tumorous and adjacent non-tumorous tissues of LUAD patients by qRT-PCR (c) and western blotting (d, e). f Immunohistochemistry staining and analysis of the levels of RNF115 in tumorous and neighboring normal tissues from LUAD patients. Scale bar, 100 μm. g Kaplan-Meier plot for survival rate of LUAD patients with differential RNF115 expression (high or low) over 60 months