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. 2021 Jan 14;10:608082. doi: 10.3389/fonc.2020.608082

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Copyright © 2021 Zhang, Wang, Wang, Liu, Li, Yu, Wu, Liang, Yu and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OTSSP167 induces cell cycle arrest at the G2/M phase. (A, B) The U87 and LN229 cells were stained with PI after 24 h of OTSSP167 treatment. The results were assessed by flow cytometry. (C, D) Quantitative analysis of cell cycle phase distribution of cells in the control and the OTSSP167 treatment groups. (E) Western blotting analysis of cell cycle-related protein levels in U87 and LN229 cells treated with OTSSP167 for 24 h with indicated antibodies. All the Data are presented as means ± SEM. ***P<0.001.