Table 3.
Active site residues comparison table.
| SARS CoV2 -RDRP (PDB ID:7BTF) | Poliovirus -RDRP (PDB ID:2ILY) |
|---|---|
| Ser759 | Gly327 |
| Asp618 | Asp233 |
| Ser549 | Arg163 |
| Ala547 | Glu161 |
| Ala554 | Ser173 |
| Gly683 | Gly289 |
| Thr687 | Thr293 |
| Asn691 | Asn297 |
| Cys622 | Tyr237 |
| Lys621 | Gly236 |
| Lys545 | Lys159 |
| Arg555 | Arg174 |
| Ser682 | Ser282 |
| Ser681 | Pro287 |
| Thr556 | Leu175 |
| Val557 | Ile176 |
| Lys551 | Lys167 |
| Ala547 | Glu161 |
| Asp760 | Asp328 |
| Asp623 | Asp238 |
| Arg553 | Lys172 |
| Ala558 | Glu177 |
| Tyr619 | Tyr234 |
| Pro620 | Thr235 |
| Arg624 | Ala239 |
| Asp684 | Unknown |
| Thr680 | Met286 |
| Ser759 | Gly327 |
| Ala550 | Ser164 |
| Glu857 | Ser290 |
| Tyr925 | Unknown |
| Asp761 | Asp329 |
Active site residues of SARS-CoV-2-RdRp (PDB ID: 7BTF) and poliovirus-RdRp (PDB ID: 2ILY) are represented.
Note* Comparable residues in the table were results of the superimposition analysis of SARS-CoV-2-RdRp (PDB ID: 7BTF) and poliovirus-RdRp (PDB ID: 2ILY).