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. 2021 Jan 28;39(2):135–143. doi: 10.1038/s41587-021-00814-w

Acquired approvals

Product Current owner Previous developer Mode of acquisition Indication
Sarclisa (isatuximab-irfc) Sanofi Immunogen Licensed product Third-line multiple myeloma
Vyepti (eptinezumab-jjmr) Lundbeck (Valby, Denmark) Alder BioPharmaceuticals Bought Alder for $1.95 billion in 2019 Migraine prevention
Tukysa (tucatinib) Seagen Array BioPharma via Cascadian Therapeutics Bought Cascadian for $614 million in 2018 Advanced HER2-positive breast cancer
Tepezza (teprotumumab-trbw) Horizon Therapeutics Genmab via River Vision and Roche Bought River Vision for $145 million in 2017 Thyroid eye disease
QWO (Clostridium histolyticum collagenase) Endo BioSpecifics Technologies Bought BioSpecifics for $540 million in 2020 Cellulite
Zeposia (ozanimod) Bristol Myers Squibb Celgene Bought Celgene for $74 billion in 2019 Relapsing multiple sclerosis
Byfavo (remimazolam) Paion (Aachen, Germany) GlaxoSmithKline via CeNeS Pharmaceuticals Bought CeNeS for $22 million in 2008 Procedural sedation
Xeglyze (abametapir) Dr. Reddy’s Laboratories HatchTech Licensed product Head lice infestation
Tecartus (brexucabtagene autoleucel) Gilead Science Kite Pharma Bought Kite for $11.9 billion in 2017 Advanced mantle cell lymphoma