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. Author manuscript; available in PMC: 2021 Jan 28.
Published in final edited form as: Cell Rep. 2020 Nov 17;33(7):108398. doi: 10.1016/j.celrep.2020.108398

Figure 2. Microglia-Tissue Consensus Module Microglia Disease Time Course and Pathway Annotation.

Figure 2.

(A) Protein-protein interactions (PPIs) among the top 150 module genes (ranked by kME) with associated Gene Ontology pathway labeled, as shown (GO-Elite [Zambon et al., 2012], Z score > 2).

(B) Model showing microglia transitions across progressive disease stages based on the annotation of microglia-tissue consensus modules (MNMs).

See also Figure S2.