Fig. 10.

Schematic showing the steps involved in the detection of Interleukin-6 (IL-6) using the paper-based smart plasmonic biosensor (a) Immunosensing scheme in which capture Ab (antibody) is immobilized onto the filter paper, and binding of IL-6 to capture Ab is detected using gold nanoparticles conjugated with avidin and biotinylated antibodies (b) Imaging of the colored spot on the filter paper with the help of virtual frame using smartphone (c) Detection screen displaying the automatic identification of the region of interest using augmented reality (d) The result screen indicating the pixel intensity value. Reproduced with permission from Ref. [154].