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. 2021 Jan 28;34(5):553–561. doi: 10.1016/j.echo.2021.01.012

Table 4.

Definition of MIS-C

Age < 21 y with fever (>38.0°C or subjective) for ≥24 h
Laboratory evidence of inflammation
Multisystem (more than two) organ involvement
No alternative plausible diagnoses
Positive for current or recent SARS-CoV-2 infection or exposure within the 4 weeks before the onset of symptoms (noting that because infection may occur from an asymptomatic contact, children and their caregivers may not even know that they had been infected)