Table 2.
Characteristics of 40–49-year-old Japanese men by equol producing status (>83 nM) (n 274) in the Electron-Beam Computed Tomography and Risk Factor Assessment among Japanese and U.S. Men in the Post World War II Birth Cohort study from 2002 to 2007
(Mean values and standard deviations; medians and interquartile ranges (IQR); percentages are presented for continuous and categorical variables; 50th and 75th percentiles)
| Equol-producers (n 43) | Equol non-producers (n 231) | |||
|---|---|---|---|---|
| Mean | sd | Mean | sd | |
| Age (years) | 45·7 | 2·6 | 44·9 | 2·9 |
| BMI (kg/m2) | 23·8 | 2·7 | 23·7 | 3·2 |
| Systolic BP (mmHg) | 123·3 | 16·7 | 124·4 | 15·7 |
| Hypertension (%) | 18·6 | 25·5 | ||
| Total cholesterol (mmol/l) | 5·7 | 0·9 | 5·6 | 0·9 |
| LDL-cholesterol (mmol/l) | 3·6 | 0·9 | 3·5 | 0·9 |
| HDL-cholesterol (mmol/l) | 1·4 | 0·3 | 1·4 | 0·4 |
| Glucose (mmol/l) | ||||
| Median | 5·9 | 5·7 | ||
| IQR | 5·6, 6·2 | 5·4, 6·1 | ||
| C-reactive protein (nmol/l) | ||||
| Median | 2·7 | 3·5 | ||
| IQR | 1·4, 6·1 | 1·4, 6·8 | ||
| Diabetes (%) | 0·0 | 6·1 | ||
| Current smokers (%) | 41·9 | 48·5 | ||
| Pack-years of smoking (years) | ||||
| Median | 18·0 | 17·3 | ||
| IQR | 2·8, 30·0 | 2·0, 28·0 | ||
| Alcohol (g/d) | ||||
| Median | 20·0 | 12·0 | ||
| IQR | 2·9, 37·0 | 15·1, 36·0 | ||
| n-3 Fatty acids (%)† | 8·26 | 2·75 | 9·33 | 2·39* |
| Meat consumption ≥2-3 times/week | 22·1 | 20·9 | ||
| Education (years) | ||||
| Median | 16·0 | 16·0 | ||
| IQR | 12·0, 16·0 | 12·0, 16·0 | ||
| Medication | ||||
| Hypertension (%) | 2·3 | 4·8 | ||
| Lipid (%) | 4·7 | 2·6 | ||
| Exercise ≥1 h/week (%) | 30·2 | 25·1 | ||
| Dietary isoflavones (nm)‡ | ||||
| Median | 803·7 | 449·8 | ||
| IQR | 278·9, 1346·6 | 186·7, 1030·7* | ||
| CCS | ||||
| 50th percentile | 0·0 | 0·0 | ||
| 75th percentile | 0·0, 1·03 | 0·0, 1·5 | ||
| Prevalence of CCS ≥10 (%) | 2·3 | 10·9 | ||
BP, blood pressure; CCS, coronary calcium scores.
Significant at <0·0.
n-3 Fatty acids were estimated as the sum of serum levels of EPA and DHA.
Dietary isoflavones were estimated as the sum of serum levels of daidzein and genistein.