Fig. 1. YAP1 immunoreactivity in benign cirrhotic liver, HCCs and hepatoblastoma.
(A, B) The HCC case showing positive YAP1 in the ductules surrounding the cirrhotic nodules (A, H&E staining), but negative in the HCC cells and normal hepatocytes. (C) Another HCC case showing focally and moderately positive YAP1 in the HCC cells. (D) A hepatoblastoma case showing moderately to strongly positive YAP1 in the tumor cells. (A–D, 400×). D denotes ductule in Fig. 1A. Abbreviations: YAP1, Yes-associated protein-1; HCC, hepatocellular carcinoma; H&E, hematoxylin-eosin.