Figure 2. Complement activation induced PMT in a swine model of I/R injury.

A. Representative pictures of PDGRβ and α-SMA staining performed on paraffin sections at T0 (before ischemia) and 24 h after reperfusion (T24 CTRL). At T0, PDGFRβ⁺/αSMA⁺ cells were rarely detectable (zoomed image) and α-SMA was localized in the arterial wall (white arrow). After 24 h from I/R injury, the number of these cells dramatically increased (T24 CTRL). Magnification 630x. B. Results are expressed as median ± IQR of five independent pigs for each group. The statistical analysis was performed using the Mann-Whitney test. Modified from Figure 4 in Castellano et al. (2018) . License: (http://creativecommons.org/licenses/by/4.0/).