Table 5.
The Comparison With the Other Clinical Study of Oxaliplatin Based Regimen as Adjuvant Chemotherapy
| CapOX | mFOLFOX6 | |||
|---|---|---|---|---|
| Hospital visits | Every 3 weeks | Every 2 weeks | ||
| Port-catheter | Not require | Require | ||
| Our study | XELOXA | MOSAIC | JOIN | |
| Dose intensity | ||||
| Oxaliplatin | 76.5% | 87.0% | >80.0% | 78.2% |
| Capesitabine | 75.8% | 84.0% | – | – |
| 5-FU | – | – | 84.4% | 87.7% (bolus), 78.1% (infusion) |
| Treatment completion | 82.9% | 69.0% | 74.7% | 67.0% |
| DFS rate | 63.8% (five-year) | 66.1% (five-year) | 73.3% (five-year) | – |
| OS rate | 71.0% (five-year) | 77.6% (five-year) | 78.5% (six-year) | – |
| HFS (>grade 3) | 0% | 5.0% | – | – |
| PSN (>grade 3) | 17.1% | 9.0% | 12.4% | 5.8% |
HFS, hand–foot syndrome; PSN, peripheral sensory neuropathy.